Sc1000結合內動脈選項，利用原尾套血壓分析儀器的模塊化技術，現在也包括了直接的血壓測量！通過精密儀表放大器和微型壓力傳感器，這種創新的設計允許壓力傳感盡可能接近源頭，防止常常在臺式傳感器上發生的的錯誤。另外，這一獨特的系統讓您可以輕松地獲得動物的前儀表的皮下輸液端口壓力讀數。端口消除了經常發生的外部導管問題，使動物可以正常住房。

SC1000IA內動脈系統操作，通過一系列連接部件以提供即時和準確的結果?？刂茊卧B接到儀表放大器，儀表方法器通過電纜連接到壓力傳感器。壓力測試針放置在壓力傳感器上，它允許直接訪問動物皮下輸液端口。此外，如果需要的話，可以通過壓力傳感器隔對動物進行注射。

新的SC1000IA動脈血壓分析系統提供了精確的、很容易獲得的直接血壓測量。它的簡單和經濟實惠的設計，現在可以提供兩種形式的血壓分析，以確保更準確的結果。
 　
SC1000IA控制單元:
與SC1000IA系統配合使用的輸液端口有多種尺寸，從“微小”的小鼠端口到大鼠或其他動物使用的大尺寸的端口都有。雙端口導管也可同時進行輸液和壓力測量。
　　
內動脈操作系統:
同樣的技術，在原SC1000IA控制單元中也能夠進行直接血壓測量，并提供準確的結果?？刂茊卧B接到儀表放大器，儀表放大器連接到壓力傳感器。然后壓力測試針進入皮下輸液端口立即獲得直接的血壓讀數。

SC1000IA控制單元:
與SC1000IA系統配合使用的輸液端口有多種尺寸，從“微小”的小鼠端口到大鼠或其他動物使用的大尺寸的端口都有。雙端口導管也可同時進行輸液和壓力測量。

SC1000IA控制單元:
與SC1000IA系統配合使用的輸液端口有多種尺寸，從“微小”的小鼠端口到大鼠或其他動物使用的大尺寸的端口都有。雙端口導管也可同時進行輸液和壓力測量。

Sc1000結合內動脈選項，利用原尾套血壓分析儀器的模塊化技術，現在也包括了直接的血壓測量！通過精密儀表放大器和微型壓力傳感器，這種創新的設計允許壓力傳感盡可能接近源頭，防止常常在臺式傳感器上發生的的錯誤。另外，這一獨特的系統讓您可以輕松地獲得動物的前儀表的皮下輸液端口壓力讀數。端口消除了經常發生的外部導管問題，使動物可以正常住房。

The Role ofAngiotensin II in Experimental Acute Kidney Injury and Cardiorenal FailureSofia J?nsson2019

J?nsson, S. 2019. The Role of Angiotensin II inExperimental Acute Kidney Injury and Cardiorenal Failure. Digital ComprehensiveSummaries of Uppsala Dissertations from the Faculty of Medicine 1554.… (More)

A companion tothe preclinical common data elements for physiologic data in rodent epilepsymodels. A report of the TASK3 Physiology Working Group of the ILAE/AES JointTranslational Task ForceJan A. Gorter, Erwin A. van Vliet, +7 authors Astrid NehligEpilepsiaopen2018

The International League Against Epilepsy/AmericanEpilepsy Society (ILAE/AES) Joint Translational Task Force created the TASK3working groups to create common data elements (CDEs) for various… (More)

Neuronalexpression of the mitochondrial protein prohibitin confers profoundneuroprotection in a mouse model of focal cerebral ischemia.Anja Kahl, Corey J. Anderson, +4 authors Ping ZhouJournalof cerebral blood flow and metabolism…2017

The mitochondrial protein prohibitin (PHB) has emergedas an important modulator of neuronal survival in different injury modalities .We previously showed that viral gene transfer of PHB protects… (More)

Physiological,morphological, and ecological tradeoffs influence vertical habitat use ofdeep-diving toothed-whales in the BahamasTrevor W Joyce, John William Durban, +5 authors Lisa Taylor BallancePloS one2017

Dive capacity among toothed whales (suborder: Odontoceti)has been shown to generally increase with body mass in a relationship closelylinked to the allometric scaling of metabolic rates. However,… (More)

Impact ofAngiotensin Type 1A Receptors in Principal Cells of the Collecting Ducton Blood Pressure and Hypertension.Daian Chen, Johannes Stegbauer, +5 authors Thomas M. CoffmanHypertension2016

The main actions of the renin-angiotensin system tocontrol blood pressure (BP) are mediated by theangiotensin type 1 receptors (AT1Rs). The major murine AT1R isoform, AT1AR, isexpressed throughout… (More)

Moderateadditive effects of endothelin receptor A blockade in Ren-2 transgenic ratssubjected to various types of RAS blockade.Ivana Vaně?ková, Lenka ?ezá?ová, Jaroslav Kunes?, Josef ZichaLifesciences2016

AIMS Chronic endothelin receptor A (ETA) blockadelowered blood pressure (BP) by decreasingangiotensin-dependent vasoconstriction and attenuating calcium influx. Wetested whether the addition of… (More)

The Role Of TCells In Postmenopausal HypertensionDennis P Pollow2016

The rate and severity of hypertension are much lowerin women than men of a similar age. However, the incidence of hypertension andits complications increase dramatically after menopause, matching… (More)

IndividualVariation in Diet Response: Health Effects of Dietary Interventions on Micewith Diverse Genetic BackgroundsWilliam Thomas Barrington2016

BARRINGTON, WILLIAM THOMAS. Individual Variation inDiet Response: Health Effects of Dietary Interventions on Mice with DiverseGenetic Backgrounds (Under the direction of David Threadgill).… (More)

Vasculardysfunctions in the isolated aorta of double-transgenic hypertensive micedeveloping aortic aneurysmLudovic Waeckel, Cécile Badier-Commander, +6 authors Michel FélétouPflügersArchiv - European Journal of Physiology2014

Angiotensin-II and oxidative stress are involved inthe genesis of aortic aneurysms, a phenomenon exacerbated by endothelial nitricoxide synthase (eNOS) deletion or uncoupling. The purpose of this… (More)

Abstracts of theSICB 2014 Annual Meeting, January 3?7, 2014, Austin, TX.Harvey S. MuddIntegrativeand comparative biology2014

emily.m.abbott@gmail.com The effect of musclerelaxation rate on tendon recoil during energy dissipating tasks Series elasticelements, such as tendons and aponeuroses, can amplify muscle power,… (More)

The Role ofAngiotensin II in Experimental Acute KidneyInjury and Cardiorenal FailureSofia J?nsson2019

J?nsson, S. 2019. The Role ofAngiotensin II inExperimental Acute Kidney Injury and Cardiorenal Failure.Digital ComprehensiveSummaries of Uppsala Dissertations from the Faculty ofMedicine 1554.… (More)

A companion tothe preclinical common data elements forphysiologic data in rodent epilepsymodels. A report of the TASK3 PhysiologyWorking Group of the ILAE/AES JointTranslational Task ForceJan A. Gorter, Erwin A. van Vliet, +7 authors Astrid NehligEpilepsiaopen2018

The International League Against Epilepsy/AmericanEpilepsySociety (ILAE/AES) Joint Translational Task Force created the TASK3workinggroups to create common data elements (CDEs) for various… (More)

Neuronalexpression of the mitochondrial proteinprohibitin confers profoundneuroprotection in a mouse model of focal cerebralischemia.Anja Kahl, Corey J. Anderson, +4 authors Ping ZhouJournalof cerebral blood flow and metabolism…2017

The mitochondrial protein prohibitin(PHB) has emergedas an important modulator of neuronal survival in differentinjury modalities .We previously showed that viral gene transfer of PHBprotects… (More)

Physiological,morphological, and ecological tradeoffsinfluence vertical habitat use ofdeep-diving toothed-whales in the BahamasTrevor W Joyce, John William Durban, +5 authors Lisa Taylor BallancePloS one2017

Dive capacity among toothed whales(suborder: Odontoceti)has been shown to generally increase with body mass in arelationship closelylinked to the allometric scaling of metabolic rates.However,… (More)

Impact ofAngiotensin Type 1A Receptors in Principal Cellsof the Collecting Ducton Blood Pressure andHypertension.Daian Chen, Johannes Stegbauer, +5 authors Thomas M. CoffmanHypertension2016

The main actions of the renin-angiotensin system tocontrol blood pressure (BP)are mediated by theangiotensin type 1 receptors (AT1Rs). The major murine AT1Risoform, AT1AR, isexpressed throughout… (More)

Moderateadditive effects of endothelin receptor Ablockade in Ren-2 transgenic ratssubjected to various types of RAS blockade.Ivana Vaně?ková, Lenka ?ezá?ová, Jaroslav Kunes?, Josef ZichaLifesciences2016

AIMS Chronic endothelin receptor A(ETA) blockadelowered blood pressure (BP) by decreasingangiotensin-dependentvasoconstriction and attenuating calcium influx. Wetested whether the additionof… (More)

The Role Of TCells In Postmenopausal HypertensionDennis P Pollow2016

The rate and severity of hypertensionare much lowerin women than men of a similar age. However, the incidence ofhypertension andits complications increase dramatically after menopause,matching… (More)

IndividualVariation in Diet Response: Health Effects ofDietary Interventions on Micewith Diverse Genetic BackgroundsWilliam Thomas Barrington2016

BARRINGTON, WILLIAM THOMAS. IndividualVariation inDiet Response: Health Effects of Dietary Interventions on Mice withDiverseGenetic Backgrounds (Under the direction of David Threadgill).… (More)

Vasculardysfunctions in the isolated aorta ofdouble-transgenic hypertensive micedeveloping aortic aneurysmLudovic Waeckel, Cécile Badier-Commander, +6 authors Michel FélétouPflügersArchiv - European Journal of Physiology2014

Angiotensin-II and oxidative stress areinvolved inthe genesis of aortic aneurysms, a phenomenon exacerbated byendothelial nitricoxide synthase (eNOS) deletion or uncoupling. The purpose ofthis… (More)

Abstracts of theSICB 2014 Annual Meeting, January 3?7,2014, Austin, TX.Harvey S. MuddIntegrativeand comparative biology2014

emily.m.abbott@gmail.com The effect ofmusclerelaxation rate on tendon recoil during energy dissipating tasks Serieselasticelements, such as tendons and aponeuroses, can amplify musclepower,… (More)

Novel thromboxane A2 analog-inducedIUGR mouse model
C Fung, A Brown, J Cox… - … Originsof Health …, 2011

The Na+/Ca2+ exchanger-1 mediates leftventricular dysfunction in mice with chronic intermittent hypoxia
L Chen, J Zhang, X Hu… - Journalof Applied …, 2010

 - Am Physiological Soc ... with the animalsconscious and restrained, using a tail-cuff system (Hatteras Instruments, model... B: mean BP (MBP) measured by intra-arterial catheter at week 8 (n = 1517... The separation of BP and myocardial changes provides direct evidencesuggesting that the mechanisms ...

- Cambridge Univ Press ... We alsomeasured hepatic tumor necrosis factor-alpha (TNFa) levels to assess U-46619'sdirect effect on the fetal liver ... We used a tail-cuff system (HatterasInstruments Model MC4000, Cary, NC, USA) that has been demonstrated tocorrelate strongly with intra-arterial BP in ...

Vascular endothelial growth factorreceptor 2 controls blood pressure by regulating nitric oxide synthaseexpression
CS Facemire, AB Nixon, R Griffiths, H Hurwitz… - …, 2009

- Am Heart Assoc ... In the dose-findingexperiments, systolic BPs were measured in conscious mice using a computerizedtail-cuff system (Hatteras Instruments) after 2 ... This method has beenvalidated previously and correlates well with direct measurements ofintra-arterial pressure. ...

Angiotensin II AT1 blockade reduces thelipopolysaccharide-induced innate immune response in rat spleen
E Sánchez-Lemus, J Benicky… - AmericanJournal of …, 2009

- Am Physiological Soc ... bloodpressure was recorded with an intra-arterial interface (SC1000IA, HatterasInstruments, Cary ... There were no significant changes in intra-arterial bloodpressure after LPS administration, and the endotoxin did ... Although ourresults are indicative of direct effects of LPS on the ...